Use Cases

What people use it for

Analysis workflows, intelligence products, and combined pipelines. Each one produces a full report with methods, findings, and complete provenance.

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CORTEX+SYNAPSE

Combined Workflows

Synapse intelligence flowing into Cortex analysis. Published evidence meets your experimental data in a single integrated pipeline.

Synapse dossier + omics data

Target Validation

Validate biological targets by integrating published evidence with your own experimental data. Detect where your findings converge with, or contradict, the broader evidence base.

Evidence convergence map showing where your data aligns with published literature findings

Contradiction report surfacing conflicts between your results and existing evidence, contextualized by species, model, and disease stage

Translational gap analysis highlighting where evidence exists across in vitro, in vivo, and clinical stages, and where it doesn't

Advance or deprioritize targets based on convergent evidence from your data and the full published record.

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Synapse safety profile + treated/control omics

Toxicogenomics & Safety

Evaluate compound safety by combining your experimental toxicogenomics data with pharmacovigilance signals, clinical trial adverse events, and known class liabilities.

Integrated risk assessment combining your expression changes with FAERS signals and clinical trial safety data

Organ-system safety map overlaying your compound's expression signature onto known toxicity markers

Class liability detection identifying whether observed signals match patterns from related compounds

Prioritize compounds with cleaner safety profiles and flag liabilities before they become expensive.

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SYNAPSE

Synapse Intelligence

No data upload required: intelligence from literature and databases. Enter a gene, disease, or compound and get a scored evidence profile.

Gene or protein name

Assemble a comprehensive evidence-backed profile for any gene or protein target. Assess druggability, map disease associations, identify where the translational chain has gaps, and surface conflicting evidence.

Complete target dossier with druggability assessment, disease associations ranked by evidence score, and clinical trial landscape

Translational gap analysis showing evidence coverage from in vitro through clinical stages

Contradiction report with conflicting findings contextualized by species, tissue, dose, and disease stage

Prioritize targets by evidence strength before committing validation resources.

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Disease name or indication

Disease Landscape Assessment

Map an indication comprehensively: validated targets, the competitive treatment landscape, biomarker coverage, genetic basis, and where unmet need remains.

Validated target list ranked by evidence strength with mechanism-of-action annotations

Treatment landscape with drugs grouped by treatment line and cross-referenced against trial data

Unmet medical need score integrating epidemiology, treatment gaps, and genetic underpinnings

Evaluate indication attractiveness and identify whitespace opportunities.

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Disease or target

Competitive Intelligence

Understand who is working on what, how far along they are, and what outcomes they're seeing, for any disease area.

Approved drugs with mechanism, indication, and market context

Pipeline map by phase with sponsor, trial design, and primary endpoints

Biomarker-drug pairings and trial outcome summaries

Define your differentiation strategy based on a clear view of the competitive field.

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Target or compound

Safety Profiling

Evaluate target safety liabilities early by consolidating pharmacovigilance signals, clinical adverse events, off-target activity, and class-wide patterns.

Organ-level risk assessment combining FAERS signals with clinical trial safety data

Off-target liability panel from polypharmacology screens

Class-wide liability analysis identifying patterns shared across related mechanisms

Flag target liabilities early, before they become expensive surprises downstream.

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CORTEX

Cortex Analysis

Bring your data. Cortex runs rigorous multi-method analysis. From differential expression to pathway enrichment, every result comes with full provenance.